Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression
نویسندگان
چکیده
منابع مشابه
Epithelial to mesenchymal transition concept in Cancer: Review article
Owing to this fact that most of the mortalities in cancers are as a result of metastasis, study on the involved pathways in metastasis including Epithelial to mesenchymal transition (EMT) would be so critical and important. Up to date, several extensive studies have been carried out to determine the correlation between EMT and cancer and their results have shown that the EMT plays pivotal role ...
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Pancreatic ductal adenocarcinoma (PDAC) continues to be one of the most lethal human malignancies, with median survival of less than one year and overall 5-year survival of less than 5%. There is increasing evidence for contribution of epithelialmesenchymal transition (EMT) to pancreatic cancer metastasis and to treatment resistance. In this chapter we will review the role of EMT in pancreatic ...
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Herein, we review the current findings of how a variety of accessory cells could participate in shaping the tumor microenvironment and supporting the mechanisms by which cancer cells undertake the epithelial-mesenchymal transition (EMT). EMT, a complex of phenotypic changes, promotes cancer cell invasion and creates resistance to chemotherapies. Among the accessory cells present in the EMT, imm...
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ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2015
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2015.494